Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, antihistamines such as cetirizine, diphenhydramine drugs for sleep or anxiety such as alprazolam, diazepam, zolpidem muscle relaxants, and narcotic pain relievers such as codeine. Ketoconazole, a potent inhibitor of CYP3A4, at a dose of 400 mg QD for 5 days, increased the AUC and C max of Ziprasidone by about 35 to 40%. Other inhibitors of CYP3A4 would be expected to have similar effects. This is more common when you first start taking ziprasidone. Schotte A, Janssen PF, Gommeren W, et al. March 1996.
Ziprasidone is not approved for use in psychotic conditions related to dementia. Ziprasidone may increase the risk of death in older adults with dementia-related conditions. What is ziprasidone, and how does it work mechanism of action? Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company CHLIC. In Arizona, individual HMO plans are insured by Cigna HealthCare of Arizona, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company CGLIC or their affiliates see a that insure or administer group HMO, dental HMO, and other products or services in your state. Group Universal Life GUL insurance plans are insured by CGLIC. Life other than GUL accident, critical illness, and disability plans are insured or administered by Life Insurance Company of North America, except in NY, where insured plans are offered by Cigna Life Insurance Company of New York. All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.
Keep Ziprasidone hydrochloride capsules and all medicines out of the reach of children. The risk of developing tardive dyskinesia and the likelihood that it will become irreversible are believed to increase as the duration of treatment and the total cumulative dose of antipsychotic drugs administered to the patient increase. However, the syndrome can develop, although much less commonly, after relatively brief treatment periods at low doses. Nemeroff CB, Lieberman JA, Weiden PJ, et al. November 2005.
Ziprasidone, and all patients experiencing these reactions were reported to recover completely. Upon appearance of rash for which an alternative etiology cannot be identified, Ziprasidone should be discontinued. Side Effects List Imipramine Hcl side effects by likelihood and severity. Ziprasidone 5, 20, and 40 mg twice daily none of the dose groups was statistically superior to placebo on any outcome of interest. Because of this, Ziprasidone hydrochloride should be used only after your doctor has considered this risk for Ziprasidone hydrochloride against the risks and benefits of other medications available for treating schizophrenia.
QTdrugs List, AZCERT, Inc. There was no evidence to suggest that these developmental effects were secondary to maternal toxicity. Antipsychotic drugs which include Ziprasidone hydrochloride may cause somnolence, postural hypotension, and motor and sensory instability, which could lead to falls and, consequently, fractures or other injuries. There are some medications that may be unsafe to use when taking Ziprasidone hydrochloride, and there are some medicines that can affect how well Ziprasidone hydrochloride works. Do not share this medication with others. Miceli JJ, Anziano RJ, Robarge L, Hansen RA, Laurent A 2000. Elderly patients with a diagnosis of psychosis related to dementia. Ziprasidone hydrochloride capsules are not approved for the treatment of these patients. During pregnancy, this medication should be used only when clearly needed. Please refer to the patient package insert. To assure safe and effective use of Ziprasidone hydrochloride capsules, the information and instructions provided in the patient information should be discussed with patients.
Because Ziprasidone is highly metabolized, with less than 1% of the drug excreted unchanged, renal impairment alone is unlikely to have a major impact on the pharmacokinetics of Ziprasidone. You might have to take different kinds of drugs for other symptoms, too. PANSS on two consecutive days. Ziprasidone was significantly superior to placebo in time to relapse, with no significant difference between the different dose groups. There were insufficient data to examine population subsets based on age and race. Examination of population subsets based on gender did not reveal any differential responsiveness. It affects how you think and behave. This can show up in different ways and at different times, even in the same person. The illness usually starts in late adolescence or young adulthood. Woosley RL, Romero KA. www. This information is generalized and not intended as specific medical advice. Severe. These medicines may interact and cause very harmful effects and are usually not taken together. British Journal of Clinical Pharmacology. Ziprasidone's activity is primarily due to the parent drug. The multiple-dose pharmacokinetics of Ziprasidone are dose-proportional within the proposed clinical dose range, and Ziprasidone accumulation is predictable with multiple dosing. Elimination of Ziprasidone is mainly via hepatic metabolism with a mean terminal half-life of about 7 hours within the proposed clinical dose range. Steady-state concentrations are achieved within one to three days of dosing. Ziprasidone hydrochloride capsules contain a monohydrochloride, monohydrate salt of Ziprasidone. In the rat study, there was no evidence of an increased incidence of tumors compared to controls. In male mice, there was no increase in incidence of tumors relative to controls. Ziprasidone may cause a a condition consisting of abnormal muscle movements, including tremor, shuffling, and uncontrollable movements 1 in 20 patients. These metabolic changes include hyperglycemia, dyslipidemia, and body weight gain. While all of the drugs in the class have been shown to produce some metabolic changes, each drug has its own specific risk profile. This medicine may be harmful if swallowed. Since Ziprasidone has the potential to impair judgment, thinking, or motor skills, patients should be cautioned about performing activities requiring mental alertness, such as operating a motor vehicle including automobiles or operating hazardous machinery until they are reasonably certain that Ziprasidone therapy does not affect them adversely. ipratropium
Ziprasidone is unlikely to interfere with the metabolism of drugs metabolized by cytochrome P450 enzymes. Your spouse or partner is cheating on you. Roland Seifert; Thomas Wieland; Raimund Mannhold; Hugo Kubinyi; Gerd Folkers July 17, 2006. Ziprasidone should be used with particular caution in patients with known cardiovascular disease history of myocardial infarction or ischemic heart disease, heart failure or conduction abnormalities cerebrovascular disease, or conditions which would predispose patients to hypotension dehydration, hypovolemia, and treatment with antihypertensive medications. For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. Heinz Lüllmann; Klaus Mohr 2006. Undesirable alterations in lipids have been observed in patients treated with atypical antipsychotics. Pooled data from short-term, placebo-controlled studies in schizophrenia are presented in Tables 3-4. eboc.info telfast
Ziprasidone hydrochloride is available as capsules Ziprasidone hydrochloride for oral administration. Ziprasidone is a psychotropic agent that is chemically unrelated to phenothiazine or butyrophenone antipsychotic agents. It has a molecular weight of 412. As with other antipsychotics, long-term use of ziprasidone may lead to a potentially irreversible condition called tardive dyskinesia involuntary movements of the jaw, lips, and tongue. Recently, the FDA required the manufacturers of some atypical antipsychotics to include a warning about the risk of and with atypical antipsychotics. Its intramuscular injection form is approved for acute agitation in schizophrenic patients for whom treatment with just ziprasidone is appropriate. Citrome, L; Yang, R; Glue, P; Karayal, ON June 2009. "Effect of ziprasidone dose on all-cause discontinuation rates in acute schizophrenia and schizoaffective disorder: a post-hoc analysis of 4 fixed-dose randomized clinical trials. QTc interval have been associated with the occurrence of torsade de pointes and with sudden unexplained death. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Dizziness caused by a drop in your blood pressure may occur with Ziprasidone hydrochloride, especially when you first start taking this medication or when the dose is increased. If this happens, be careful not to stand up too quickly, and talk to your doctor about the problem. Neuroleptic Malignant Syndrome NMS has been reported in association with administration of antipsychotic drugs. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status, and evidence of autonomic instability irregular pulse or blood pressure, tachycardia, diaphoresis, and cardiac dysrhythmia. Additional signs may include elevated creatinine phosphokinase, myoglobinuria rhabdomyolysis and acute renal failure. QTc interval, including 1 bradycardia; 2 hypokalemia or hypomagnesemia; 3 concomitant use of other drugs that prolong the QTc interval; and 4 presence of congenital prolongation of the QT interval. PDF. FDA. July 19, 2000. And if you think that strangers are going to hurt you, you may feel like staying inside or being alone.
Since medications of the same drug class as Ziprasidone hydrochloride may interfere with the ability of the body to adjust to heat, it is best to avoid situations involving high temperature or humidity. Stinging, burning, irritation, dryness, or redness at the application site may occur. Geodon ziprasidone hydrochloride US prescribing information. Pfizer Inc. Is ziprasidone available as a generic drug? People with schizophrenia who get counseling are also more likely to stick with their medications. If prescribed by your doctor, use this medication for your current condition only. Do not use it later for other unless told to do so by your doctor. A different medication may be necessary in those cases. Ziprasidone. There were confounding factors that may have contributed to the occurrence of seizures in many of these cases. One case of priapism was reported in the premarketing database. While the relationship of the reaction to Ziprasidone use has not been established, other drugs with alpha-adrenergic blocking effects have been reported to induce priapism, and it is possible that Ziprasidone may share this capacity. Severe priapism may require surgical intervention. There are many products available. Many can be purchased without a prescription. Some products require a prescription. Consult your doctor or on the choice of the product that is best for you. purchase eutirox quit
Patients with an established diagnosis of diabetes mellitus who are started on atypical antipsychotics should be monitored regularly for worsening of glucose control. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. Because of its potential for inducing hypotension, Ziprasidone may enhance the effects of certain antihypertensive agents. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. This medication may increase a certain natural substance made by your body. This drug may also rarely cause significant and a rise in your blood or triglyceride levels. Ziprasidone hydrochloride is a type of prescription medicine called a psychotropic, also known as an atypical antipsychotic. Ziprasidone hydrochloride can be used to treat symptoms of schizophrenia. Additionally, population pharmacokinetic evaluation of patients in controlled trials has revealed no evidence of clinically significant age or gender-related differences in the pharmacokinetics of Ziprasidone. Dosage modifications for age or gender are, therefore, not recommended. Even when you feel better, keep taking your medicine. If you stop, your delusions will probably come back. About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. This summary contains important information about Ziprasidone hydrochloride capsules. It is not meant to take the place of your doctor's instructions. Read this information carefully before you take Ziprasidone hydrochloride capsules. Ask your doctor or pharmacist if you do not understand any of this information or if you want to know more about Ziprasidone hydrochloride capsules. This medication can cause birth defects, according to animal studies, although this side effect has not been confirmed in humans. Tell your doctor if your condition persists or worsens after 7 days or if you think you may have a serious medical problem. What are the side effects of ziprasidone? primperan how to purchase pharmacy
Lifetime carcinogenicity studies were conducted with Ziprasidone in Long Evans rats and CD-1 mice. This medication may rarely cause a very serious condition called neuroleptic malignant syndrome NMS. Given the primary CNS effects of Ziprasidone, caution should be used when it is taken in combination with other centrally acting drugs. Ziprasidone 40 and 80 mg twice daily with placebo, both dose groups were superior to placebo on the BPRS total score, the BPRS psychosis cluster, the CGI severity score and the PANSS total and negative subscale scores. Although 80 mg twice daily had a numerically greater effect than 40 mg twice daily, the difference was not statistically significant. Tissue culture experiments indicate that approximately one-third of human breast cancers are prolactin-dependent in vitro, a factor of potential importance if the prescription of these drugs is contemplated in a patient with previously detected breast cancer. Neither clinical studies nor epidemiologic studies conducted to date have shown an association between chronic administration of this class of drugs and tumorigenesis in humans; the available evidence is considered too limited to be conclusive at this time. Consult your doctor before breast-feeding. Table 6 enumerates the incidence, rounded to the nearest percent, of treatment-emergent adverse reactions that occurred during acute therapy up to 6 weeks in predominantly patients with schizophrenia, including only those reactions that occurred in 2% or more of patients treated with Ziprasidone and for which the incidence in patients treated with Ziprasidone was greater than the incidence in placebo-treated patients. In animal studies Ziprasidone demonstrated developmental toxicity, including possible teratogenic effects at doses similar to human therapeutic doses. Do not change your dose or stop taking your medicine without your doctor's approval. You'll learn to test whether you're having delusions and how to ignore voices inside your head. Although the prevalence of the syndrome appears to be highest among the elderly, especially elderly women, it is impossible to rely upon prevalence estimates to predict, at the inception of antipsychotic treatment, which patients are likely to develop the syndrome. Whether antipsychotic drug products differ in their potential to cause tardive dyskinesia is unknown. If you have any health problems, consult your doctor or pharmacist before using this product. QT prolongation, recent acute myocardial infarction, uncompensated heart failure, or cardiac arrhythmia. Journal of Central Nervous System Disease. Hyperglycemia and diabetes mellitus, in some cases extreme and associated with ketoacidosis or hyperosmolar coma or death, have been reported in patients treated with atypical antipsychotics. There have been few reports of hyperglycemia or diabetes in patients treated with Ziprasidone hydrochloride. Although fewer patients have been treated with Ziprasidone hydrochloride, it is not known if this more limited experience is the sole reason for the paucity of such reports. Assessment of the relationship between atypical antipsychotic use and glucose abnormalities is complicated by the possibility of an increased background risk of diabetes mellitus in patients with schizophrenia and the increasing incidence of diabetes mellitus in the general population. Given these confounders, the relationship between atypical antipsychotic use and hyperglycemia-related adverse reactions is not completely understood. Precise risk estimates for hyperglycemia-related adverse reactions in patients treated with atypical antipsychotics are not available.
Ziprasidone hydrochloride capsules are indicated for the treatment of schizophrenia. Older adults may be more sensitive to the side effects of this drug, especially dizziness, uncontrolled movements, and QT prolongation see above. Ziprasidone 20 and 60 mg twice daily with placebo, only the 60 mg dose was superior to placebo on the BPRS total score and the CGI severity score. This higher dose group was not superior to placebo on the BPRS psychosis cluster or on the SANS. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Tschoner A, Engl J, Rettenbacher M, et al. January 2009. If you notice any of these symptoms in your newborn especially during their first month, tell the doctor right away. Only your doctor can know if Ziprasidone hydrochloride capsules are right for you. Ziprasidone hydrochloride capsules may be prescribed for you if you have schizophrenia. Any patient treated with atypical antipsychotics should be monitored for symptoms of hyperglycemia including polydipsia, polyuria, polyphagia, and weakness. Patients who develop symptoms of hyperglycemia during treatment with atypical antipsychotics should undergo fasting blood glucose testing. In some cases, hyperglycemia has resolved when the atypical antipsychotic was discontinued; however, some patients required continuation of antidiabetic treatment despite discontinuation of the suspect drug. It is greater than 99% bound to plasma proteins, binding primarily to albumin and α 1-acid glycoprotein. The in vitro plasma protein binding of Ziprasidone was not altered by warfarin or propranolol, two highly protein-bound drugs, nor did Ziprasidone alter the binding of these drugs in human plasma. Thus, the potential for drug interactions with Ziprasidone due to displacement is minimal. Retrieved June 4, 2015. Extrapyramidal Symptoms EPS The incidence of reported EPS which included the adverse reaction terms extrapyramidal syndrome, hypertonia, dystonia, dyskinesia, hypokinesia, tremor, paralysis and twitching for Ziprasidone-treated patients in the short-term, placebo-controlled schizophrenia trials was 14% vs. 8% for placebo. Objectively collected data from those trials on the Simpson-Angus Rating Scale for EPS and the Barnes Akathisia Scale for akathisia did not generally show a difference between Ziprasidone and placebo. Daniel DG, Zimbroff DL, Potkin SG, Reeves KR, Harrigan EP, Lakshminarayanan M May 1999. Let your doctor know right away if you notice an irregular heartbeat or have any dizziness or fainting episodes. Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Proliferative changes in the pituitary and mammary glands of rodents have been observed following chronic administration of other antipsychotic agents and are considered to be prolactin-mediated. Adverse reactions related to high blood sugar hyperglycemia sometimes serious, have been reported in patients treated with atypical antipsychotics. There have been few reports of hyperglycemia or diabetes in patients treated with Ziprasidone hydrochloride, and it is not known if Ziprasidone hydrochloride is associated with these reactions. Patients treated with an atypical antipsychotic should be monitored for symptoms of hyperglycemia. estreva canada buy
Retrieved June 19, 2015. Who Should Take Ziprasidone Hydrochloride Capsules? NMS has been reported with other anti-psychotic drugs. QT prolongation and arrhythmia. Hypokalemia may result from diuretic therapy, diarrhea, and other causes. The systemic of ziprasidone is 100% when administered intramuscularly and 60% when administered orally without food. Many people using this medication not have serious side effects. The efficacy of oral Ziprasidone in the treatment of schizophrenia was evaluated in 5 placebo-controlled studies, 4 short-term 4- and 6-week trials and one maintenance trial. All trials were in adult inpatients, most of whom met DSM III-R criteria for schizophrenia. Each study included 2 to 3 fixed doses of Ziprasidone as well as placebo. Four of the 5 trials were able to distinguish Ziprasidone from placebo; one short-term study did not. Although a single fixed-dose haloperidol arm was included as a comparative treatment in one of the three short-term trials, this single study was inadequate to provide a reliable and valid comparison of Ziprasidone and haloperidol. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Ziprasidone is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Ziprasidone is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 5HT2 dopamine Type 2 D2 1 and 2 adrenergic, and H1 histaminergic receptors. Ziprasidone acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Ziprasidone. Ziprasidone's antagonism of muscarinic M1-5 receptors may explain its anticholinergic effects. Ziprasidone's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Ziprasidone's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. This drug has also been used in combination with other medication to treat depression. Ziprasidone patients compared to no median weight change in placebo patients. Ziprasidone hydrochloride capsules, 40 mg are size '4' capsules with dark blue opaque cap and dark blue opaque body, imprinted axially with "LU" on cap and "V52" on body in black ink, containing off-white to pinkish granular powder. Because Ziprasidone hydrochloride can cause sleepiness, be careful when operating machinery or driving a motor vehicle. You are currently taking medications that should not be taken in combination with Ziprasidone, for example, dofetilide, sotalol, quinidine, other Class Ia and III anti-arrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, pimozide, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol or tacrolimus. Cardiovascular monitoring should commence immediately and should include continuous electrocardiographic monitoring to detect possible arrhythmias. If antiarrhythmic therapy is administered, disopyramide, procainamide, and quinidine carry a theoretical hazard of additive QT-prolonging effects that might be additive to those of Ziprasidone. can you buy diflucan tablets in australia
It is not known whether Ziprasidone or its metabolites are excreted in human milk. It is recommended that women receiving Ziprasidone should not breastfeed. It is essential to periodically monitor serum electrolytes in patients for whom diuretic therapy is introduced during Ziprasidone treatment. Persistently prolonged QTc intervals may also increase the risk of further prolongation and arrhythmia, but it is not clear that routine screening ECG measures are effective in detecting such patients. Wash and dry your hands before using. Clean and dry the affected area. If you are using the lotion or foam, shake it well just before using. If you are using the spray, check the product package to see if it needs to be shaken before each use. Apply a small amount of medication to the affected area and gently rub in, usually up to 4 times a day or as directed by your doctor or the product package. Dosage and length of treatment depends on the type of condition being treated. Do not bandage, cover, or wrap the area unless directed to do so by your doctor. People with paranoid delusions are unreasonably suspicious of others. This can make it hard for them to hold a job, run errands, have friendships, and even go to the doctor. Prolongation of the QTc interval is associated in some other drugs with the ability to cause torsade de pointes-type arrhythmia, a potentially fatal polymorphic ventricular tachycardia, and sudden death. In many cases this would lead to the conclusion that other drugs should be tried first. This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages. Ziprasidone and placebo patients, respectively. Ziprasidone with valproate is unlikely due to the lack of common metabolic pathways for the two drugs.
Ziprasidone is similar chemically to Risperidone. In 1987, Ziprasidone was first synthesized on the central research campus in Groton, Connecticut. If you become pregnant while taking ziprasidone, call your doctor. Ziprasidone may cause problems in newborns following delivery if it is taken during the last months of pregnancy. You should not breastfeed if you are taking ziprasidone. Nicolson, SE; Nemeroff, CB December 2007. Patients with neutropenia should be carefully monitored for fever or other symptoms or signs of infection and treated promptly if such symptoms or signs occur. There are no adequate and well-controlled studies in pregnant women. Ziprasidone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. The possibility of a suicide attempt is inherent in psychotic illness and close supervision of high-risk patients should accompany drug therapy. Prescriptions for Ziprasidone should be written for the smallest quantity of capsules consistent with good patient management in order to reduce the risk of overdose. Tell your doctor if you plan to do vigorous exercise or be exposed to extreme heat. Ziprasidone has not been evaluated or used to any appreciable extent in patients with a recent history of myocardial infarction or unstable heart disease. Patients with these diagnoses were excluded from premarketing clinical studies. Baldassano CF, Ballas C, Datto SM, et al. February 2003. An in vitro enzyme inhibition study utilizing human liver microsomes showed that Ziprasidone had little inhibitory effect on CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4, and thus would not likely interfere with the metabolism of drugs primarily metabolized by these enzymes. This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. If you overheat, quickly look for a place to cool down and rest. Use this on the only. However, not use it on the face or underarms unless directed to do so by your doctor. Some products are meant to be used on the scalp for various conditions. To correctly use these products, follow the directions on the product package. Its biological half-life time is 10 hours at doses of 80-120 milligrams. What Is Ziprasidone Hydrochloride? Retrieved February 2, 2016. Withdrawal of antipsychotic drugs after long-term therapy should always be gradual and closely monitored to avoid the risk of acute withdrawal syndromes or rapid relapse. astelin
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Geodon. Pfizer had illegally promoted Geodon and caused false claims to be submitted to government health care programs for uses that were not medically accepted indications. The civil settlement also resolves allegations that Pfizer paid kickbacks to health care providers to induce them to prescribe Geodon, as well as other drugs. This was the largest civil fraud settlement in history against a pharmaceutical company. Some side effects can be serious. PDF. FDA Center For Drug Evaluation And Research. May 26, 1998.
Delayed-onset drug reaction called drug reaction with eosinophilia and systemic symptoms DRESS can occur with Ziprasidone. Signs of DRESS may include rash, fever, and swollen lymph nodes. Other severe cutaneous adverse reactions SCAR such as Stevens-Johnson syndrome can occur with Ziprasidone. Signs of Stevens-Johnson syndrome may include rash with blisters which could include ulcers in mouth, skin shedding, fever and target-like spots in the skin. DRESS and other SCAR are sometimes fatal; therefore, tell your doctor immediately if you experience any of these signs. The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.
The FDA approved ziprasidone as a treatment for in February 2001. What is the most important safety information I should know about Ziprasidone hydrochloride? EPS. Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever, and primary central nervous system CNS pathology.
Ziprasidone hydrochloride capsules, 60 mg are size '3' capsules with white opaque cap and white opaque body, imprinted axially with "LU" on cap and "V53" on body in black ink, containing off-white to pinkish granular powder. Holter monitoring may be useful. Class Effect: Symptoms of dystonia, prolonged abnormal contractions of muscle groups, may occur in susceptible individuals during the first few days of treatment. Ziprasidone hydrochloride and have their WBC followed until recovery.